Metabolic Engineering and Functional Genomics
Fall Semester only
| 6 credits
| Elective
Majors:
Biology,
Biotechnology,
Genetics,
and
Molecular Biology
A lecture/lab course that gives the students a fundamental understanding of the interplay between the many different intracellular reactions, and especially how the fluxes through the different pathways are regulated; with special focus on pathways leading to industrially relevant products like primary metabolites, antibiotics, industrial enzymes, and pharmaceutical proteins. A central aspect of the course is to identify the optimal strategy for introducing directed genetic changes in the microorganisms with the aim of obtaining better production strains. Analysis of the interaction between different cellular reactions is a central element in the course, and tools from functional genomics will therefore be described. This will involve tools like DNA arrays, proteomics and bioinformatics.
This is a Technical University of Denmark course open to DIS students. Please ensure you read the full details on taking external courses through DIS.
Prerequisites
One year of biology and one semester of chemistry at the university level, plus an introductory course in molecular biology/genetics OR completion of your university’s prerequisites for an upper-level molecular biology/genetics course.
Instructors
-
Irina Borodina
Ph.D. (Biotechnology, Technical University of Denmark, 2007). M.Sc. (Biotechnology, Technical University of Denmark, 2004). B.Sc. (Chemical Engineering, Kaunas University of Technology, 2001). Post-doctoral researcher at Technical University of Denmark since 2007. With DIS since 2010.
